QUALITIDE

What is Nonapeptide-1?

Nonapeptide-1, also known as Melanostatine™, is a synthetic biomimetic peptide that mimics a portion of the α-MSH (alpha-Melanocyte Stimulating Hormone). Designed to reduce melanin overproduction, it works by blocking MC1-R receptors on melanocytes, helping to diminish dark spots and even out skin tone—making it an ideal skin brightening peptide for modern cosmetic formulations.

Key Benefits of Nonapeptide-1

Nonapeptide-1 for Skin Brightening

By selectively inhibiting melanin synthesis, Nonapeptide-1 promotes a more radiant, luminous complexion without disrupting natural skin function.

Nonapeptide-1 Pigment Reduction Peptide

This peptide acts as a melanogenesis regulator, effectively reducing pigmentation caused by UV damage, melasma, freckles, and PIH (post-inflammatory hyperpigmentation).

Nonapeptide-1 vs Hydroquinone

Unlike hydroquinone, Nonapeptide-1 offers a non-toxic, non-irritating solution for skin lightening. It preserves melanocyte health while preventing excess pigment, making it safer for long-term use across all skin types.

Nonapeptide-1 Dark Spot Cream Benefits

Perfect for formulating dark spot correctors and pigmentation-reducing creams, this ingredient visibly reduces sunspots and discoloration within 28 days of regular use.

How It Works

MC1-R Receptor Antagonism

Nonapeptide-1 competes with α-MSH at melanocyte receptors (MC1-R), blocking signal transduction and limiting melanin production at the source.

Tyrosinase Inhibition

By reducing MC1-R activation, it indirectly suppresses tyrosinase activity, a key enzyme in the pigment production pathway, leading to lighter skin with fewer dark spots.

Functions

• Skin Whitening Agent – Lightens complexion without cytotoxicity
• Skin Conditioning – Smooths texture and tone
• Hair Conditioning – Supports healthy scalp environments in hair care
• Post-UV Care – Helps reverse pigment changes caused by sun exposure

Applications

Use Nonapeptide-1 in:

• Dark spot creams and serums
• Non-toxic skin brightening treatments
• Melasma and sunspot-reduction products
• Post-acne hyperpigmentation skincare
• Hair care serums for scalp support

Technical Specifications

• INCI: Nonapeptide-1
• Synonym: Melanostatine™
• CAS No.: 158563-45-2
• FDA UNII: 64W45420K5
• Solubility: Water-soluble
• Suggested Usage: 0.1–2.5%

Where to Buy Nonapeptide-1 Peptide?

Looking for where to buy Nonapeptide-1 peptide? We provide high-purity, cosmetic-grade Nonapeptide-1 raw material for research, formulation, and private label skincare product development.

Why Choose Nonapeptide-1?

Nonapeptide-1 offers a safe, effective alternative to harsh depigmenting agents like hydroquinone. With its smart mechanism targeting melanin at the source, it brightens skin, fades dark spots, and evens tone—without irritation or damage.

Make it your go-to pigment reduction peptide for next-generation dark spot correction and skin brightening products.

Acetyl Tetrapeptide-5 (Eyeseryl®)

Acetyl Tetrapeptide-5, commonly known by its trademark Eyeseryl®, is a clinically backed cosmetic peptide solution designed to visibly reduce under-eye puffiness, eye bags, and dark circles. Sourced from naturally derived amino acids, this tetrapeptide improves lymphatic circulation, reduces water retention, and increases skin elasticity for a refreshed and youthful eye contour.

Acetyl Tetrapeptide-5 (Eyeseryl) Benefits

• Reduces the appearance of under-eye bags and puffiness
• Improves skin elasticity in the delicate periorbital region
• Visibly decreases the appearance of dark circles
• Strengthens skin for long-lasting firming and protective effects
• Suitable for sensitive skin and daily eye care use

Mechanism of Action

Eyeseryl® peptide targets the physiological causes of puffiness:

• Enhances lymphatic drainage to reduce fluid buildup
• Minimizes capillary permeability, decreasing localized swelling
• Helps restore firmness and smoothness in the under-eye skin

These actions make it an ideal ingredient in anti-fatigue and anti-aging eye formulations.

Clinical & In Vivo Results

• 70% reduction in puffiness within 28 days
• Noticeable improvement in as few as 14 days
• 30% increase in skin elasticity in just 30 days
• Reduction in dark circle visibility in a majority of test subjects

Eyeseryl vs Dipeptide-2 Differences

• Eyeseryl® targets water retention and elasticity, acting on lymphatic drainage and vascular permeability.
• Dipeptide-2 primarily supports lymphatic circulation and ACE inhibition, more focused on edema.

These peptides can be complementary, but Eyeseryl® stands out for multifunctional eye area rejuvenation.

Eyeseryl Peptide Anti-Puffiness Use

Eyeseryl peptide is widely recognized for its anti-puffiness use in advanced skincare formulations targeting the delicate eye area. By enhancing lymphatic drainage and reducing capillary permeability, Eyeseryl effectively diminishes swelling and fluid retention under the eyes, making it a key ingredient in serums and creams designed to combat puffiness and refresh tired-looking eyes.

Specifications

• INCI Name: Acetyl Tetrapeptide-5
• Synonym: EYESERYL®
• Sequence: Ac-β-Ala-His-Ser-His-OH
• Molecular Formula: C₂₀H₂₈N₈O₇
• Molecular Weight: 492.5 g/mol
• CAS Number: 820959-17-9
• FDA UNII: D1HW9N9QBX
• Functions: Anti-puffiness | Anti-dark circles | Firming | Protective

Where to Buy Eyeseryl Peptide

Looking for a reliable source of Eyeseryl peptide for under-eye bags or to include in your eye cream or serum formulations? Buy Eyeseryl® peptide anti-puffiness use online now from our trusted marketplace for cosmetic-grade peptides and active ingredients.

Acetyl Tetrapeptide-3 for Hair Growth

Acetyl Tetrapeptide-3, also known as Folixyl® or Capixyl®, is a biomimetic peptide derived from a growth factor. It plays a key role in stimulating hair growth by promoting the synthesis of collagen and laminin within the hair follicle. These structural proteins strengthen the follicle, supporting healthier and fuller hair.

Capixyl Peptide Anti-Hair Loss Mechanism

This active ingredient works by:

• Enhancing collagen I and III synthesis to reinforce hair follicle anchoring.
• Stimulating laminin to improve cell structure and follicular stability.
• Supporting dermal papilla renewal to combat the stiffening of hair follicle sheaths — a common cause of hair thinning and loss.

Clinical studies have shown Capixyl peptide anti-hair loss activity by increasing hair density in as little as 7 days, outperforming other common treatments.

Folixyl Peptide Benefits for Skin

In addition to its scalp benefits, Folixyl peptide also supports skin rejuvenation:

• Enhances extracellular matrix support.
• Promotes cell adhesion and tissue repair.
• May improve elasticity and firmness in topical applications.

Capixyl vs Minoxidil Hair Regrowth

In clinical comparisons:

• Capixyl was shown to offer faster visible results in hair density.
• Unlike Minoxidil, Capixyl works by improving follicle structure naturally without hormonal interference.
• Capixyl is better suited for sensitive scalps due to its low-irritation formula.

Where to Buy Capixyl (Acetyl Tetrapeptide-3)

Looking to buy Capixyl or Folixyl peptides online? We offer high-purity Acetyl Tetrapeptide-3 backed by detailed documentation and third-party analysis — ideal for cosmetic formulations targeting hair growth and anti-aging.

Product Specifications

• INCI Name: Acetyl Tetrapeptide-3
• Synonyms: Folixyl®, Capixyl®
• Sequence: Ac-Lys-Gly-His-Lys-NH2 (Ac-KGHK)
• Molecular Formula: C₂₂H₃₉N₉O₅
• Molecular Weight: 492.49 g/mol
• CAS Number: 820959-17-9
• Purity: ≥98%
• Form: Lyophilized powder